A win today will give West Indies cricketers a 3-0 series win in the T20 International series against South Africa.
The game starts at 2pm at Sabina Park, Jamaica.
On Saturday the regional side got a 16 run victory against the visitors.
They won opening match by 28 runs last week Thursday.
Both sides are using the series as preparation ahead of the ICC T20 World Cup in June and America.